The Genesis of the Institute

The first miracle drug, Penicillin was extracted from fungus.  Many anti-rejection drugs used for organ transplants all originated from fungi.  "Lovastatin," the drug used for lowering cholesterol comes from the King Oyster Mushroom.

Chemical Synthesis of 9 (Z) - Octadecenamide and its Hypolipidemic Effect: A bioactive agent found in the essential oil of Mountain Celery Seeds.  Conclusively, oleamide is a potent hypolidemic agent as regarding its effects on decreasing serum TG, TC, LDL-C and heptic TG.  Serum TG reflects thyroid abnormalities and thyroid function and is a sensitive marker of iodine deficiency in a population.

Reading peer reviewed medical journals and research studies funded by the National Institute of Health, National Science Foundation and other foundations that publish the results of in vivo, in vitro and clinical trials on mushrooms, fruits and vegetables brought the idea to form this Institute.  There is an abundance of very good research available that is not being mapped and put together to present the connecting pathways and mechanisms that cause various chemical reactions within the human body from the food we consume.  We continually strive to develop a better understanding of the chemistry.  There are challenges in understanding complex biological and chemical relationships within experimental data or models from multiple data sources.   It is an ongoing process to interprete, disseminate and analyze data to create a picture as to cause and affect for a reseacher and health care provider.  A mission is to help those with this challenge to help fight and prevent disease.

Our investigations include the collaboration with other researchers on the mechanisms of the complex chemistry contained within plants and organisms in nature.  The initial research started by looking at the vast biochemistry of specific strains of various species of medicinal mushrooms and how it impacts cell biology and immunology in humans and animals.  As we harvested different types of hybrid strains of medicinal mushrooms that were used in studies at various universities, we gave them to the friends and family with serious health problems. What we found was truly remarkable, most specific health issues usually abated quickly.  One person with prostate cancer had a PSA level of 18, (an indicator of cancer). After two weeks of taking the medicinal mushrooms, the PSA had dropped to 12, and after two more weeks it was at 9. Our observations show that dosage can make a difference, in that 22 grams a day versus 32 grams a day would increase the outcomes by fifty percent.

The team of scientists came to two realizations; first, that the mushrooms clearly abate serious health problems, and second, the mushrooms have no toxic effects on the body.  Studies show there is no chronic or acute toxicity. Cell nucleus studies show no detrimental effects and DNA showed no mutations. Pregnant animal studies demonstrated there is no detriment to fetal development, and no LD50, a measure of toxicity that has never been shown. Medicinal mushrooms apparently produce no harmful side effects.  So in essence most people can eat pounds of mushrooms as food with no side effects.

Compare this result to chemotherapy drugs which have limited positive effects in arresting cancers. Unfortunately, they can damage the liver and kidneys, (the filters of the body), as well as other organs in the body.  Ultimately, the side effects catch up with the patient who then becomes nauseated, becomes thin, loses hair, and may be laid up in a hospital on IV’s.

We cultured hybrid species of mushrooms with medicinal values with the same substrates by each research team. These unique steroid-like molecules from the Hybrid strain 502HLM pass through the blood-brain barrier and causes nerve re-growth in the brain, according to clinical studies conducted in Japan. Clinical experiments in Japan showed actual re-growth of a patient’s severed spinal cord in published data in 2003, and clearly showed marked improvement of elderly patients with Dementia and Alzheimer’s, and this Hybrid strain (502HLM) treatment exceeded any of the four pharmaceutical drugs currently on the markets.  The hybrid mushroom strain contain chemistry which causes the re-growth of liver tissue.  Currently, it is used for treatment of cirrhosis of the liver and also has strong anti-cancer properties.

Consumption of the fungal chemistry in foods, done on a regular basis, will ultimately improve the user's health.  The diversity of mushroom chemistry is extreme and holds tremendous health opportunities if consumed or added to food products.


The cutting edge of nutritional science provides hope for new, less invasive and less harmful therapies. Numerous research and clinical studies have demonstrated that the consumption of various medicinal mushrooms specie strains have resulted in supporting the body's ability to fight disease with anecdotal outcomes of total remission from many diseases, including certain types of cancer.  These clinical studies used formulaic blends of medicinal mushrooms in the whole or as extracts, sometimes in combination with Western medical treatments.  In addition to the results of scientific research, an increasing number of individuals have become convinced of the miraculous potential of various strains of medicinal mushroom species by personally witnessing the success.  The methods and pathways have been theorized and further study needs to be done to determine what chemistry stops the metastasis.  Reducing the expression of TKs5 protein in cancer cells also inhibits metastatic tumor growth in animal models.  The protein TKs5 controls the formation of invadopodia in cancer cells. We have become acquainted from anecdotal evidence with men and women with cancer, who, even after chemotherapy, had little hope for recovery.  Review from anecdotal studies from Europe and Asia have proven to repeat themselves with patients here in the United States.  Some of these individuals, after consuming a specially created formula of specific hybrids strains of medicinal mushrooms grown on unique substrates over a three month period, experienced a reduction in markers, tumor growth or the shrinkage of tumors in lungs, brain, thyroid, prostate, colon, ovaries, breasts, bones and with some achieved a complete remission of the disease.  Based on our extensive research from the compiled science in the industry and with our collaboration with other researchers blends were formulated of various hybrid strains of various medicinal mushroom species with recommended diet changes to affect the human chemistry in such a way to boost and balance the immune system and to correct flaws in mammalian chemistry.   

A growing number of hospitals and clinics in the United States have introduced integrative medical departments that provide a more “holistic” treatment of patients with debilitating diseases so that patients can benefit from the full spectrum of healing arts.  Integrative medicine practitioners represent multiple disciplines which include acupuncturists, nutritionists, Ayurvedic, Chinese and homeopathic physicians.  Many of the physicians who design treatment plans have been trained in Western, Eastern, and complementary medical disciplines.  There is great interest in these programs across the country as knowledge continues to grow on the use of food and food supplements as adjuncts for healing.   These new centers for integrative medicine have embraced the use of adding medicinal mushrooms to the diets of patients who will benefit from doing so.